Before this study, investigators did not know how autophagy is in play during involution and how it is different in the reversible versus irreversible phase of involution.
Baboons, closely resembling humans in physiology, serve as vital models in various research areas such as neonatal lung disease, atherosclerosis, pregnancy, nutrition, liver disease, brain imaging, epilepsy, and xenotransplantation.
Hamsters play a crucial role in various research areas like cancer, reproduction, virology, diabetes, and cardiovascular diseases due to their physiological similarities to humans, particularly in lipid metabolism and atherogenesis.
Fruit flies have helped to develop drugs designed to treat a range of diseases from skin infections and genetic disorders to pneumonia, and meningitis. Some of the recent research with fruit flies has focused on understanding Alzheimer’s disease, Huntington’s disease, spastic paraplegia, cancer, obesity and insomnia.
The common marmoset, due to its size and similarities with humans, is crucial in safety, reproductive biology, neuroscience, and drug development studies. In multiple sclerosis research, its immunological likeness aids therapy development.
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Titi monkeys, with their unique capacity for social attachment, are pivotal in studying neurotransmitters' role in attachment biology. Their involvement in visualizing oxytocin receptors aids research in autism spectrum disorder due to biological similarities to humans.
A whole-virus vaccine to confront Ebola, the rare but often fatal hemorrhagic disease that periodically erupts in sub-Saharan Africa, may soon be one step closer to the clinic.
Immune cell studies take aim at organ transplant rejection, autoimmune diseases