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Home / Animal Groups / Rodents

Animal Group: Rodents

Rodents, like mice and rats, are popular models for biomedical research due to their anatomical, physiological and genetic similarities to humans. Some advantages for using rodents include ease of maintenance, their small size, and short life cycles that enable researchers to study the full course of diseases and therapies.

Another plus is that mice and rats offer an abundance of genetic resources.  Mice share almost 95% of their genes with humans. Their genome is well known and able to be manipulated so that models of specific human diseases may be studied.

Because of these characteristics, mice continue to play a vital part in the discovery and development of treatments and cures for cancer, Alzheimer’s, cardiovascular disease, diabetes, and many infectious diseases.

Other rodents needed for research include hamsters, gerbils, guinea pigs, and chinchillas.

Did you Know?

A rat can fall as far as 50 feet and land unharmed.

Rats have been invaluable to cardiovascular medicine, neural regeneration, wound healing, diabetes and transplantation.

30 Nobel Prizes needed rats for the awarded contribution to science.

A Shrew must eat 80-90 % of their own body weight in food daily.

Shrews are easily startled and will jump, faint, or drop dead at a sudden noise.

Studies needing mice were awarded 30 Nobel prizes.

Guinea pig studies lead to the discovery of Vitamin C, the tuberculosis bacterium and adrenaline.

About 10% of rat genes are shared in mice but absent in humans.

Guinea pigs have contributed to 23 Nobel prizes for medicine.

Explore Rodents by Species

Mouse Thumbnail

Mouse

Mice are pivotal in medical progress, facilitating treatments for cancer, heart disease, neurodegenerative disorders like Parkinson's, and psychiatric conditions such as anxiety and schizophrenia. Read More →

Rat Thumbnail

Rat

Rats are essential models in research, aiding studies in physiology, immunology, pharmacology, nutrition, behavior, and learning, leading to medical advancements in obesity, diabetes, cancer, cardiovascular, neurological, and immune-related diseases. Read More →

Hamster Thumbnail

Hamster

Hamsters play a crucial role in various research areas like cancer, reproduction, virology, diabetes, and cardiovascular diseases due to their physiological similarities to humans, particularly in lipid metabolism and atherogenesis. Read More →

Guinea Pig Thumbnail

Guinea Pig

Guinea pigs, resembling humans in bacterial infection symptoms and immune response, have aided research for over 200 years, advancing treatments for lung, ear, eye, artery, stomach, intestine diseases, including tuberculosis. Read More →

Chinchilla Thumbnail

Chinchilla

Chinchillas serve as vital models for auditory system research due to their physiological similarities to humans, aiding advancements in acoustic studies and offering insights into middle ear infections and other areas like respiratory infections and ototoxicity. Read More →

Japanese shrew Thumbnail

Japanese shrew

The Japanese Shrew serves as a crucial model for Congenital Sucrase-Isomaltase Deficiency (CSID), mirroring symptoms seen in humans, aiding research into digestion disorders affecting both infants and adults. Read More →

Animals in Research

Exiting the Tunnel

Tunnels can be used to comfortably handle mice. Injections can also be provided in a stress-free manner using the tunnel. After the…

Animals in Research

Transporting a Mouse using Cupped Handling

One way to ensure a positive experience for mice in research is to use the cupped handling technique when transporting them to…

Animals in Research

Square Tunnel

Tunnels allow mice to carry out natural behaviors like hiding and climbing. Some tunnels are square, making it easier for mice to…

Animals in Research

Mouse Returned to Home Cage via Tunnel

When changing or transporting a mouse back to its home cage after a procedure, tunnels help to reduce stress. The mouse is…

Animals in Research

Mouse Exam

Mice are checked every day to ensure good health. This is done daily by observing the animals through the clear cage. During…

Animals in Research

Mouse Acclimated to Tunnel

Mice like to explore and rest in tunnels. Acclimating mice to tunnels also helps handle them in a way that is comfortable…

Animals in Research

Cupped Hands to Handle Mice

Handling mice with cupped hands has been shown to reduce stress. Animals that are stress-free allow scientists to gather accurate and more…

Animals in Research

Gentle Encouragement

When using tunnels to handle mice, the animals are acclimated to the tunnel and gloved hands. Once acclimated, mice are then gently…

Animals in Research

Acclimating Mice to Tunnel Handling

The tunnel handling technique provides a safe, comfortable way for mice to be picked up and moved to another enclosure or procedure…

Animals in Research

Acclimating Mice to Humans

Ensuring mice are comfortable when handling is important for the mouse and for the science. Mice, like other animals, respond well to…

Animals in Research

Acclimating Mice to Cupped Handling

Mice are acclimated to handling to reduce stress and increase animal welfare. The cupped handling technique provides the opportunity for the mouse…

View More Rodents

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